| 產(chǎn)品編號 |
bsk11169 |
| 英文名稱 |
Human Hepcidin ELISA Kit
|
| 中文名稱 |
人鐵調(diào)素酶聯(lián)免疫試劑盒 |
| 別 名 |
HAMP; HEPC; HFE2B; LEAP1; PLTR; hepcidin antimicrobial peptide |
| 克 隆 號 |
|
| 種 屬 |
Human |
| 線性范圍 |
7.8-500 pg/mL |
| 應(yīng)用范圍 |
S/P/CC |
| 檢測限 |
4 pg/mL |
| 適用樣品基質(zhì) |
cell culture supernates, serum, and plasma. |
| 保存條件 |
Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.). |
| 注意事項(xiàng) |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 |
Hepcidin is a protein that in humans is encoded by the HAMP gene. Hepcidin is a key regulator of the entry of iron into the circulation in mammals. In states in which the hepcidin level is abnormally high such as inflammation, serum iron falls due to iron trapping within macrophages and liver cells and decreased gut iron absorption. This typically leads to anemia due to an inadequate amount of serum iron being available for developing red cells. When the hepcidin level is abnormally low such as in hemochromatosis, iron overload occurs due to increased ferroportin mediated iron efflux from storage and increased gut iron absorption.
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