產(chǎn)品編號 | IHC0682H |
英文名稱 | Human CMA1 Ready-To-Use IHC Kit |
中文名稱 | 人肥大細(xì)胞類糜蛋白酶1即用型免疫組化試劑盒 |
別 名 | chymase; CHYMASE; Alpha-chymase; Chymase 1; Chymase 1 mast cell; Chymase; Chymase heart; Chymase mast cell; CMA1; CMA1_HUMAN; CYH; CYM; EC 3.4.21.39; Mast cell chymase 1; Mast cell protease 3; Mast cell protease 5; Mast cell protease I; Mast cell protease III; Mcp-5; MCP3P; Mcpt5; MCT1; MGC119890; MGC119891; MMCP-5 |
適用樣品基質(zhì) | FFPE tissue |
保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
產(chǎn)品介紹 |
This gene product is a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Angiotensin II has been implicated in blood pressure control and in the pathogenesis of hypertension, cardiac hypertrophy, and heart failure. Thus, this gene product is a target for cardiovascular disease therapies. This gene maps to 14q11. 2 in a cluster of genes encoding other proteases. SWISS: P23946 Gene ID: 1215 |
產(chǎn)品圖片 |
Immunohistochemical analysis of paraffin embedded Human esophagus tissue slide using IHC0682H (Human CMA1 Kit).
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