| 產(chǎn)品編號(hào) | bs-7813R-Gold |
| 英文名稱 | Rabbit Anti-NEDD1/Gold Conjugated antibody |
| 中文名稱 | 膠體金標(biāo)記的神經(jīng)前體細(xì)胞表達(dá)蛋白1抗體 |
| 別 名 | GCP WD; Neural precursor cell expressed, developmentally down regulated gene 1; TUBGCP7; FLJ35902; NEDD1_HUMAN. |
| 規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
| 說 明 書 | 100ul（10nm 15nm 35nm） |
| 研究領(lǐng)域 | 細(xì)胞生物 神經(jīng)生物學(xué) 干細(xì)胞 細(xì)胞周期蛋白 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Dog, Cow, Rabbit, ) |
| 產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 72kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 0.4mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human NEDD1 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
| 保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
| 產(chǎn)品介紹 |
background: May play an important role during the embryonic development and differentiation of the central nervous system. Human NEDD1 localises to the centrosome and mitotic spindle. It binds to the components of the gamma-tubulin ring complex and target this complex to the centrosome and spindle. Function: Required for mitosis progression. Promotes thenucleation of microtubules from the spindle. Subunit: Interacts with FAM29A and gamma-tubulin. Subcellular Location: Cytoplasm, cytoskeleton, centrosome. Post-translational modifications: During mitosis, prior phosphorylation on Thr-550 by CDK1promotes subsequent phosphorylation by PLK1 on Thr-382, Ser-397,Ser-426 and Ser-637. Phosphorylated NEDD1 can interact withgamma-tubulin for targeting the gamma-tubulin ring complex (gTuRC)to the centrosome, an important step for spindle formation. Similarity: Contains 8 WD repeats. Database links: UniProtKB/Swiss-Prot: Q8NHV4.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
