| 產(chǎn)品編號(hào) | IHC0676H |
| 英文名稱 | Human StAR Ready-To-Use IHC Kit |
| 中文名稱 | 人類固醇激素合成急性調(diào)節(jié)蛋白即用型免疫組化試劑盒 |
| 別 名 | STAR; STARD1; START domain containing 1; STAR_HUMAN; START domain containing protein 1; Steroid acute regulatory protein |
| 適用樣品基質(zhì) | FFPE tissue |
| 保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
| 產(chǎn)品介紹 |
Steroidogenic acute regulatory protein (StAR) plays a significant role in cholesterol transport from the cytoplasmic outer membrane to the inner mitochondrial membrane. The 37 kDa precursor is cleaved to generate an active 28 kDa protein capable of facilitating cholesterol metabolism into pregnenolone. StAR is prevalently expressed in mitochondria of steroid-producing adrenal and gonadal tissue. Abnormalities in StAR gene expression are impacted in autosomal Lipoid Congenial Adrenal Hyperplasia (LCAH) resulting in defects in pregnenolone and cortisol synthesis. The mechanism of cholesterol binding to StAR has yet to be elucidated. SWISS: P49675 Gene ID: 6770 |
| 產(chǎn)品圖片 |
Immunohistochemical analysis of paraffin embedded Human adrenal gland tissue slide using IHC0676H (Human StAR Kit).
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